Effects of acupuncture on nutritional state of patients with stable chronic obstructive pulmonary disease (COPD): re-analysis of COPD acupuncture trial, a randomized controlled trial

July 23, 2019
Masao Suzuki,corresponding author1,3 Shigeo Muro,2 Motonari Fukui,3 Naoto Ishizaki,4 Susumu Sato,5 Tetsuhiro Shiota,6 Kazuo Endo,7 Tomoko Suzuki,1
Tadamichi Mitsuma,1 Michiaki Mishima,8 and Toyohiro Hirai5


There are an increasing number of evidences that chronic obstructive pulmonary disease (COPD) is a systemic illness and that bodyweight loss is its prominent
manifestation. We focused on the nutritional outcomes to find out the effectiveness of acupuncture on nutritional state of COPD patients and on their prognosis in our previous interventional study.

The present study is re-analysis of our previous interventional study, COPD Acupuncture Trial (CAT) published in 2012. Data from CAT was re-analyzed in terms of nutritional status, inflammatory biomarkers, and prognostic index. Nutritional states were evaluated by the measurements of body weight, body composition, and muscle strength, and the nutritional hematological examination results (retinolbinding protein (RBP), prealbumin (PA), transferrin (Tf), and hemoglobin (Hb) in serum), and inflammation biomarkers such as carboxyhemoglobin (COHb), High sensitivity C-reactive protein (Hs-CRP), Tumor Necrosis Factor-alpha (TNF-α), Interleukin 6 (IL-6), and Serum Amyloid A (SAA) were measured. The BODE index
was measured in terms of prognosis. These measurements were compared between the real acupuncture group (RAG) and the placebo acupuncture group (PAG). All data are presented as mean (SD) or mean (95% CI). The difference between baseline and final volumes was compared using analysis of covariance (ANCOVA). Moreover, correlations between nutritional hematological examination scores and inflammation biomarker parameters were assessed using Spearman’s rank correlation coefficient.

After 12 weeks, the change in body weight was significantly greater in the RAG compared with the PAG (mean [SD] difference from baseline: 2.5 [0.4] in RAG vs − 0.5 [1.4] in PAG; mean difference between the groups: 3.00, 95% CI, 2.00 to 4.00 with ANCOVA). Patients in RAG also had improvements in the results of nutritional hematological examination (RBP, PA, Tf, Hb), Inflammation biomarkers (TNF-α, IL-6, SAA, Hs-CRP, COHb) and the BODE index.

This study demonstrated some clear evidences that acupuncture can be a useful adjunctive therapy to improve nutritional state of COPD patients.

Acupuncture for Loss of Smell

May 22, 2019
58-year-old Mr Kanp is from Germany. He was on holiday in our area and staying with a friend. When he complained about his loss of sense of smell, his friend recommended he come to see me. He told me that five months ago he had a very bad cold and took antibiotics for it. After that he lost part of sense of smell. He could only sense a strange, unfamiliar smell when some odours were very strong. His throat felt uncomfortable and his taste was also affected. Doctors were not sure what caused t...
Continue reading...

Effects of Acupuncture Treatment on Fibromyalgia Symptoms, Serotonin, and Substance P Levels: A Randomized Sham and Placebo - Controlled Clinical Trial

April 29, 2019
Pain Med. 2018 Mar 1;19(3):615-628. 


The aim of this study was to evaluate the effects of acupuncture treatment on serum levels of serotonin and substance P (SP) as well as on clinical parameters in patients with fibromyalgia (FM).

This is a randomized controlled clinical trial. Seventy-five women with FM were randomized into one of three kinds of acupuncture treatment: real acupuncture group (AcG), sham acupuncture group (Sh...

Continue reading...

Can acupuncture help menopause symptoms?

March 14, 2019

Continue reading...

Acupuncture for Diarrhoea

January 14, 2019
Jacob, a 25-year-old sports therapist had suffered from diarrhoea for 10  
months. He woke up in the morning with a abdominal ache and had to go to  
the toilet 6-7 times then go again 1-2 times in the evening. He  
also got diarrhoea after doing exercise or drinking water. His tummy  
ache seemed to start from the right lower part of his abdomen and travel  
to the left side, where the urgency of going to toilet was triggered.  He suffered from chronic lower back pain in the past and it was aggra...

Continue reading...

Acupuncture's Role in Solving the Opioid Epidemic: Evidence, Cost- Effectiveness, and Care Availability for Acupuncture as a Primary, Non-Pharmacologic Method for Pain Relief and Management- White Paper 2017.

November 8, 2018

The United States (U.S.) is facing a national opioid epidemic, and medical systems are in need of non-pharmacologic strategies that can be employed to decrease the public's opioid dependence. Acupuncture has emerged as a powerful, evidence-based, safe, cost-effective, and available treatment modality suitable to meeting this need. Acupuncture has been shown to be effective for the management of numerous types of pain conditions, and mechanis...

Continue reading...